Journal: Journal of Thoracic Disease
Article Title: SNHG 12 and hsa-miR-140-5P may play an important role in the ceRNA network related to hypertrophic cardiomyopathy
doi: 10.21037/jtd-23-189
Figure Lengend Snippet: DEL, DEM, and DEG screening. (A) Red represents upregulated lncRNAs/miRNAs/mRNAs in HCM, and blue represents downregulated lncRNAs/miRNAs/mRNAs in HCM, while grey represents those not significant. (B) 93 DELs (77 up-regulated and 16 down-regulated), 163 DEMs (91 up-regulated and 72 down-regulated), and 432 DEGs were overlapped. DEL, differentially expressed long non-coding RNA; DEM, differentially expressed microRNA; mRNA, messenger RNA; DEG, differentially expressed gene; HCM, hypertrophic cardiomyopathy.
Article Snippet: LncRNA expression profiling related to HCM was conducted for 7 HCM patients and 5 disease-free individuals who were included in GSE68316 (platform: GPL20113 Capital Bio Human LncRNA Microarray v2.0; CapitalBio, Beijing, China) and for 28 HCM patients and 9 healthy donors who were included in GSE130036 (platform: GPL20795, HiSeq X Ten; Illumina, San Diego, CA, USA).
Techniques: